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Charles Wolfus

Vice President, Digital Health and Business Operations


As MyoKardia’s head of Digital Health, Charles Wolfus is on a mission to improve patient lives by applying sensors, social media, mobile technology, and artificial intelligence in clinical trials and daily life.

In 2017, Charles led MyoKardia’s multidisciplinary team in the world’s first use of commercial wearables in an interventional drug clinical study. MyoKardia’s phase 2 PIONEER-HCM clinical trial captured PPG data as an exploratory endpoint. Through subsequent machine-learning analysis MyoKardia was able to detect HCM with greater than 95% accuracy.

Charles is a recognized thought leader in the fusion of wearable technology and its use in clinical trials. He passionately believes that these technologies will improve healthcare for all. Charles has been a technology leader in biotech for nearly 20 years and a featured a speaker at international digital heath symposia. He is licensed to practice law in the State of California.

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